Picked up one of these yesterday.
The thing that initially interested me was that it's designed for 2 way midi communication: the knobs are 'endless' encoders so have no fixed start and end point, and the LED value indicators can be updated from incoming midi messages.
So the ideal outcome is that any S-gear preset change, amp A/B change, or other on screen parameter change, will automatically sync with what's displayed on the controller.
Reaper by default lacks this ability (from what I can see) but I've worked out how to send midi messages out to the controller through Reaper scripts. So.... early days still, but I am pretty confident that my S-Gear Viewer app will be able manage this syncing (I did a quick test and got the gain control synced up when I changed presets).
The other nice feature with the controller is that the knobs can be pressed, so are also buttons, which can send different midi messages. My thinking is that the Gain knob will change amp channel when pushed, the Bass knob will change Bass Switch, Treble knob: Bright Switch, Amp Drive knob (for Wayfarer) will be the Amp Drive Switch for other amps when pushed etc. This seems a great use of these buttons, and frees up the 16 dedicated buttons for something else.
It also has two 'layers' so you can have 2 completely independent mappings for all controllers.
Some fun times ahead playing with this and integrating with my S-gear Viewer app.